Transcriptome Analysis of Multiple Tissues in the Shrimp Penaeus vannamei Reveals the Typical Physiological Response to Three Pathogens

Penaeid shrimp aquaculture is impacted by various diseases. However, most published studies on physiological responses to pathogens have focused the changes in one or two tissues of infected a single pathogen, effects infecting tissue. There has been limited systematic examination similarities and differences immune multiple under pathogen infection. Here, transcriptomic three (gill, hepatopancreas hemocytes) infection white spot syndrome virus (WSSV), Vibrio parahaemolyticus acute hepatopancreatic necrosis disease (VPAHPND), decapod iridovirus 1 (DIV1) were examined provide new insights regarding important cultured shrimp, Penaeus vannamei. The results showed tissue-specific tissues. significant differentially expressed genes (DEGs) gill are mainly related environmental information processing cellular processes. DEGs hemocytes mostly involved processes, while those primarily associated with metabolism. In addition, cytoskeleton-related proteins, MAPK signaling pathway, complement coagulation level thermogenesis may play key roles shrimp–pathogen interactions across These findings shed light typical vannamei contribute sustainable development penaeid farming.